{"id":879,"date":"2017-08-07T19:12:56","date_gmt":"2017-08-07T19:12:56","guid":{"rendered":"https:\/\/dev.isrt.ac.bd\/?post_type=tribe_events&p=879"},"modified":"2017-08-07T19:12:56","modified_gmt":"2017-08-07T19:12:56","slug":"seminar-on-tuesday-may-24-2016","status":"publish","type":"tribe_events","link":"https:\/\/isrt.ac.bd\/event\/seminar-on-tuesday-may-24-2016\/","title":{"rendered":"Seminar on Tuesday, May 24, 2016"},"content":{"rendered":"

Comparison of adaptive designs for dose \u001cfinding in phase I clinical trials<\/h1>\n
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May 20, 2016 – 3:45pm<\/em><\/span><\/p>\n\n\n\n\n\n\n\n
Full Title:<\/strong><\/td>\nComparison of adaptive designs for dose \u001cfinding in phase I clinical trials<\/td>\n<\/tr>\n
Speaker:<\/strong><\/td>\nDr. M. Iftakhar Alam<\/td>\n<\/tr>\n
<\/td>\nInstitute of Statistical Research and Training, Deltin 7 Aviator গেম টাকা ইনকাম of Deltin 7, Deltin 7-1000, Bangladesh<\/td>\n<\/tr>\n
Date\/Time:<\/strong><\/td>\nTuesday, May 24, 2016<\/span>,\u00a03:30 p.m.<\/td>\n<\/tr>\n
Venue:<\/strong><\/td>\nISRT Seminar Room<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

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ABSTRACT<\/strong><\/div>\n

The Continual reassessment method is a model based procedure that has been in the literature to determine the maximum tolerated dose in phase I clinical trials. The maximum tolerated dose can also be found under the framework of D-optimum design. This paper investigates the two methods to explore any potential differences between them. Simulation studies for six plausible dose-response scenarios show that the D-optimum design can work well over the continual reassessment method in many cases. The D-optimum design has also been found to allocate doses from the extremes of design region to the patients in a trial.<\/p>\n

Keywords: Dose \u001cfinding studies; Phase I trial; Maximum tolerated dose; Continual re-assessment method; D-optimum design.<\/p>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Comparison of adaptive designs for dose \u001cfinding in phase I clinical trials May 20, 2016 – 3:45pm Full Title: Comparison of adaptive designs for dose \u001cfinding in phase I clinical … [ Read More ]<\/a><\/p>\n","protected":false},"author":5,"featured_media":0,"template":"","meta":{"_acf_changed":false,"nf_dc_page":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_tribe_events_status":"","_tribe_events_status_reason":"","footnotes":""},"tags":[],"tribe_events_cat":[15],"class_list":["post-879","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-seminar","cat_seminar"],"acf":[],"_links":{"self":[{"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/tribe_events\/879","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/tribe_events"}],"about":[{"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/users\/5"}],"version-history":[{"count":1,"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/tribe_events\/879\/revisions"}],"predecessor-version":[{"id":880,"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/tribe_events\/879\/revisions\/880"}],"wp:attachment":[{"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/media?parent=879"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/tags?post=879"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/isrt.ac.bd\/wp-json\/wp\/v2\/tribe_events_cat?post=879"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}